Dr. Clayton earned her medical degree from the University of Virginia School of Medicine, and completed an internship and residency at UVA Hospital in 1988. In addition, she served in the US Navy as medical officer, returning to the UVA faculty in 1990. Dr. Clayton is a Distinguished Fellow of the American Psychiatric Association, is certified by the American Board of Psychiatry and Neurology, and is a member of the American College of Obstetrics and Gynecology. Articles and abstracts authored by Dr. Clayton have appeared in numerous journals, including Academic Psychiatry, the American Journal of Psychiatry, Biological Psychiatry, the Journal of Clinical Psychiatry, the Journal of Sex and Marital Therapy, the Journal of Sexual Medicine, and others. She has edited with Dr. Susan Kornstein, the complete resource, Women's Mental Health: A Comprehensive Textbook. She is a Consulting Editor for the Journal of Sex & Marital Therapy, the Journal of Sexual Medicine, and the Archives of Women's Mental Health, and is on the International Advisory Board to Women's Health. She was the President of the International Society for the Study of Women's Sexual Health (ISSWSH) 2005-2007. She serves on the Board of Directors of the American Society of Clinical Psychopharmacology. She developed and validated the Changes in Sexual Functioning Questionnaire to measure sexual desire and function, which has been linguistically validated in more than 50 languages, and utilized in over 50 clinical studies. Her book on women's sexuality for the general public, Satisfaction: Women, Sex, and the Quest for Intimacy was published by Ballantine Books/Random House in January 2007. Her current research includes mood and anxiety disorders associated with reproductive-life events in women, sexual dysfunction related to illness and medications, and treatment of sexual disorders.