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Managing the Link Between Depression and Pain
Available for credit through November 12, 2008

Accreditation
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the University of Virginia School of Medicine and Discovery Health Channel. The University of Virginia School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

The University of Virginia School of Medicine and Public Health designates this educational activity for a maximum of one AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Program Overview
Depression is a common medical condition in the U.S. affecting 12 million people each year. The diagnosis of depression is difficult and frequently missed. Patients often present with physical symptoms, rather than traditional emotional symptoms of depression. Many of these physical symptoms are body aches and pains, and there is a reciprocal role between depression and painful symptoms. Research has shown the neurotransmitters serotonin and norepinephrine play a pivotal role in development of depression and associated pain. Medications targeting these two important neuromodulators have proven to be effective in the broad treatment of emotional and physical symptoms of depression. Discovery Health CME brings together a group of experts to discuss physical symptoms of depression, biochemical causes for these symptoms and appropriate treatment options for patients with depression and pain.

Acknowledgement of Commercial Support
This program is funded through an educational grant from Eli Lilly and Company.

Learning Objectives
At the conclusion of this program, participants should be able to:

• Describe the most recent epidemiology of depression.
• Recognize physical symptoms of depression.
• Describe the reciprocal roles of depression and pain.
• Understand the roles of norepinephrine and serotonin in pain and depression.
• Discuss the socioeconomic impact of untreated pain and depression.
• Review effective pharmacologic treatment strategies that target both depression and pain.
• Describe the recent physical activity recommendations.

Target Audience
This program has been developed for psychiatric, mental health, internal medicine, family practice, pediatric, dietetic and other clinicians.

Faculty Disclosure Information
As a sponsor accredited by the ACCME, it is the policy of the University of Virginia School of Medicine to require the disclosure of the existence of any significant financial interest or any other commercial supporter(s) of this activity or the manufacturer(s) of any commercial products(s) discussed in an educational presentation. Detailed disclosure will be made during the program.